Humanized anti-IL-10 antibodies for the treatment of systemic lupus erythematosus (SLE)

Humanized anti-IL-10 antibodies for the treatment of systemic lupus erythematosus (SLE)

Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (IL-10), wherein said antibody or fragment thereof is capable of being administered to a subject in the absence of an intolerable increase in the level of pro-inflammatory cytokines. Further provide...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: DAELKEN, BENJAMIN, ZUBER, CHANTAL, UHEREK, CHRISTOPH, ROTTGEN, PETER, GUTSCHER, MARCUS, CZELOTH, NIKLAS, BRUECHER, CHRISTOPH, WARTENBERG-DEMAND, ANDREA, ENGLING, ANDRE, OSTERROTH, FRANK, WESSELS-KRANZ, JUDITH
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (IL-10), wherein said antibody or fragment thereof is capable of being administered to a subject in the absence of an intolerable increase in the level of pro-inflammatory cytokines. Further provided are methods of treatment involving the use of the antibody or fragment thereof.