Monoclonal antibodies and diagnostic uses thereof

The disclosure relates to antibodies to the preferentially expressed antigen in melanoma (PRAME), and the synovial sarcoma X breakpoint 2 (SSX-2) antigens, methods of use, and diagnostic kits thereof. In exemplary embodiments, the disclosure relates to monoclonal antibodies to specific epitopes of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZHU, SUTAO, KERTESZ, NATHALIE, CHIANG, CHIH-SHENG
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The disclosure relates to antibodies to the preferentially expressed antigen in melanoma (PRAME), and the synovial sarcoma X breakpoint 2 (SSX-2) antigens, methods of use, and diagnostic kits thereof. In exemplary embodiments, the disclosure relates to monoclonal antibodies to specific epitopes of the PRAME and SSX-2 antigens and methods of using such antibodies.