Kinase inhibitors, prodrug forms thereof and their use in therapy

The present invention relates to pyrido[3,4-d]pyrimidine compounds of formula (I) suitable as kinase inhibitors, kinase inhibitors in prodrug form, their use in compositions and medicaments which are suitable for the treatment of diseases related to kinase activity such as cancers.

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Bibliographische Detailangaben
Hauptverfasser: Jamieson, Stephen Michael Frazer, Lee, Ho Huat, Denny, William Alexander, Hsu, Huai-Ling (Annie), Wilson, William Robert, Lu, Guo-Liang, Maroz, Andrej, Anderson, Robert Forbes, Patterson, Adam Vorn, Smaill, Jeffrey Bruce, Ashoorzadeh, Amir, Carlin, Kendall Marie, Mowday, Alexandra Marie
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to pyrido[3,4-d]pyrimidine compounds of formula (I) suitable as kinase inhibitors, kinase inhibitors in prodrug form, their use in compositions and medicaments which are suitable for the treatment of diseases related to kinase activity such as cancers.