5-Lipoxygenase-activating protein (FLAP) inhibitors

5-Lipoxygenase-activating protein (FLAP) inhibitors

5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP) Also described herein are 5 methods of using such FLAP modulators, alone and in combin...

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Hauptverfasser: ROPPE, JEFFREY ROGER, PRASIT, PETPIBOON PEPPI, LI, YIWEI, ZUNIC, JASMINE ELEANOR, HADDACH, MUSTAPHA, MORAN, MARK, STOCK, NICHOLAS SIMON, HUTCHINSON, JOHN HOWARD, STEARNS, BRIAN ANDREW, ARRUDA, JEANNIE M, EVANS, JILLIAN F
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP) Also described herein are 5 methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotrien.e mediated conditions c-r diseases.