Biomarkers and uses thereof

The invention of the present application is to markers of regulatory T (Treg) cells, in particular, cell surface markers of Peptidase Inhibitor 16 (PI16; SEQ ID NO: 27 & 28) and uses of those markers or compounds that bind thereto to identify or isolate Treg cells or to diagnose/prognose/treat/p...

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Bibliographische Detailangaben
Hauptverfasser:	PEDERSON, STEPHEN MARTIN, ZOLA, HEDDY, WILKINSON, BRIDGET GABRIELLE, KRUMBIEGEL, DOREEN, NICHOLSON, IAN CAMERON, SADLON, TIMOTHY JOHN, BARRY, SIMON
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention of the present application is to markers of regulatory T (Treg) cells, in particular, cell surface markers of Peptidase Inhibitor 16 (PI16; SEQ ID NO: 27 & 28) and uses of those markers or compounds that bind thereto to identify or isolate Treg cells or to diagnose/prognose/treat/prevent Treg-mediated conditions. The present invention also provides methods for identification and/or isolation of Treg cell subpopulations and such isolated populations of Treg cells.