Truncated cystine-knot proteins

The invention relates to the fields of protein chemistry, biology and medicine. More specifically, it relates to the design and preparation of proteinmimics of members of the cystine-knot growth factor superfamily. Further the invention relates to the use of these proteinmimics as a medicament or pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TIMMERMAN, PETER, HACKENG, TILMAN MATHIAS, GRIFFIOEN, ARJAN WILLEM, PUIJK, WOUTER CORNELIS
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to the fields of protein chemistry, biology and medicine. More specifically, it relates to the design and preparation of proteinmimics of members of the cystine-knot growth factor superfamily. Further the invention relates to the use of these proteinmimics as a medicament or prophylactic agent. The invention provides proteinmimics of members of the cystine-knot growth factor superfamily, preferably for use in immunogenic and/or therapeutic compositions.