Macrocyclic compounds useful as pharmaceuticals
C:\NRPortbl\DCC\ALHm2932546_m..juuL - 4IU/zU I U The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorder...
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| creator | KUBOI, YOSHIKAZU KAWAKAMI, YOSHIYUKI LI, XIANG-YI SPYVEE, MARK EGUCHI, YOSHIHITO YAMAMOTO, SATOSHI CHIBA, KENICHI WANG, JOHN (YUAN) FUJITA, MASANORI SUKURAI, HIDEKI HARMANGE, JEANRISTOPHE YONEDA, NAOKI KOTAKE, MAKOTO KAWADA, MEGUMI BOIVIN, ROCH JIANG, YIMIN DU, HONG INOUE, ATSUSHI MIZUI, YOSHIHARU SHEN, YONGUN MATSUSHIMA, TOMOHIRO CHOW, JESSE LEMELIN, CHARLES-ANDRE TANAKA, ISAO KIMURA, AKIFUMI GUSOVSKY, FABIAN GOTO, MASAKI SHIROTA, HIROSHI MURAMOTO, KENZO KAWAI, TAKATOSHI |
| description | C:\NRPortbl\DCC\ALHm2932546_m..juuL - 4IU/zU I U The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein RI-RI1 , t, X, Y, Z, and n are as defined herein. R10 O R3 JR2 n ORS n R7 Re |
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R10 O R3 JR2 n ORS n R7 Re</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Macrocyclic compounds useful as pharmaceuticals |
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