Macrocyclic compounds useful as pharmaceuticals

C:\NRPortbl\DCC\ALHm2932546_m..juuL - 4IU/zU I U The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorder...

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Hauptverfasser:	KUBOI, YOSHIKAZU, KAWAKAMI, YOSHIYUKI, LI, XIANG-YI, SPYVEE, MARK, EGUCHI, YOSHIHITO, YAMAMOTO, SATOSHI, CHIBA, KENICHI, WANG, JOHN (YUAN), FUJITA, MASANORI, SUKURAI, HIDEKI, HARMANGE, JEANRISTOPHE, YONEDA, NAOKI, KOTAKE, MAKOTO, KAWADA, MEGUMI, BOIVIN, ROCH, JIANG, YIMIN, DU, HONG, INOUE, ATSUSHI, MIZUI, YOSHIHARU, SHEN, YONGUN, MATSUSHIMA, TOMOHIRO, CHOW, JESSE, LEMELIN, CHARLES-ANDRE, TANAKA, ISAO, KIMURA, AKIFUMI, GUSOVSKY, FABIAN, GOTO, MASAKI, SHIROTA, HIROSHI, MURAMOTO, KENZO, KAWAI, TAKATOSHI
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	C:\NRPortbl\DCC\ALHm2932546_m..juuL - 4IU/zU I U The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein RI-RI1 , t, X, Y, Z, and n are as defined herein. R10 O R3 JR2 n ORS n R7 Re