Bicyclic compounds as 4B2 nicotinic acetylcholine receptor ligands

The present invention relates to novel bicyclic compounds of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a...

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Hauptverfasser: MOHAMMED, ABDUL RASHEED, JAYARAJAN, PRADEEP, RAVELLA, SRINIVASA RAO, KAMBHAMPTI, RAMA SASTRI, JASTI, VENKATESWARLU, NIROGI, RAMAKRISHNA, AHMAD, ISHTIYAQUE, SHINDE, ANIL KARBHARI, BHYRAPUNENI, GOPINADH, VEERAMALLA, SRINIVAS
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel bicyclic compounds of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. These compounds are useful in the treatment and prevention of various disorders that are related to α nicotinic receptors.