Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
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| creator | TAO, ZHI-FU DOHERTY, GEORGE A SULLIVAN, GERARD M LESSENE, GUILLAUME LAURENT PARK, CHANG H WANG, XILU ELMORE, STEVEN W HASVOLD, LISA MANTEI, ROBERT A SONG, XIAOHONG PETROS, ANDREW M DING, HONG COLMAN, PETER MALCOLM MCCLELLAN, WILLIAM J PARK, CHEOL-MIN WANG, LE KUNZER, AARON R WENDT, MICHAEL D BRUNCKO, MILAN DAI, YUJIA HEXAMER, LAURA CZABOTAR, PETER EDWARD SOUERS, ANDREW J WANG, GARY T |
| description | Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
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