Process for the preparation of vorinostat

The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.

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Bibliographische Detailangaben
Hauptverfasser: MADHUKAR S. PATIL, SANDEEP G. MEKDE, HEMANT M. MANDE, RAHUL A. BHALERAO, VINAYAK G. GORE
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.