Antibodies that Immunospecifically Bind to BLys

Abstract The present invention relates to antibodies and related molecules that immunospecifically bind to BLyS. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated 5 with aberrant BLyS expression or inappropriate function of BL...

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Hauptverfasser: RUBEN, STEVEN M, HILBERT, DAVID, CHOI, GIL H, VAUGHAN, TRISTAN, BARASH, STEVEN C
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Abstract The present invention relates to antibodies and related molecules that immunospecifically bind to BLyS. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated 5 with aberrant BLyS expression or inappropriate function of BLyS comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to BLyS. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant BLyS expression or inappropriate BLyS function 10 comprising administering to an animal an effective amount of oune or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to BLyS.