Biphenyl carboxylic acids and derivatives thereof

Biphenyl carboxylic acids and derivatives thereof

The present disclosure relates to compounds having the general Formula (I) with the definitions of R1, R2, R3, and R4 as provided herein, and/or salts thereof. The disclosure also relates to the use of such compounds for the treatment of Alzheimer's disease, and for the modulation of γ-secretas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: CHIH YUNG HO
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure relates to compounds having the general Formula (I) with the definitions of R1, R2, R3, and R4 as provided herein, and/or salts thereof. The disclosure also relates to the use of such compounds for the treatment of Alzheimer's disease, and for the modulation of γ-secretase activity.