Novel histone deacetylase inhibitors

Novel histone deacetylase inhibitors

Provided herein are novel, stilbene like compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, metabolites, prodrugs, solvates, pharmaceutically acceptable salts and compositions thereof. These compounds can inhibit HDACs and are use...

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Bibliographische Detailangaben
Hauptverfasser: MANI, KAMARAJ, NARAYANASWAMY, PUNTHALIR, RAMACHANDRAN, BALAJI, MANI, UMAMAHESWARI, PONPANDIAN, THANASEKARAN, RAJAGOPAL, SRIRAM, RAJAGOPAL, SRIDHARAN, RATHINASAMY, SURESH, KEERI, ABDUL RAHEEM, KACHHADIA, VIRENDRA, RAJENDRAN, PRAVEEN
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided herein are novel, stilbene like compounds of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, metabolites, prodrugs, solvates, pharmaceutically acceptable salts and compositions thereof. These compounds can inhibit HDACs and are useful as a therpeautic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, autoimmune diseases, skin diseases, infections, inflammation, etc.