Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors

Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. Th...

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Hauptverfasser: DESHPANDE, RAJENDRA P, WANG, HAIXIA, LI, JIE JACK, QIAN, XINHUA, ROBL, JEFFREY A, GALELLA, MICHAEL, KENNEDY, LAWRENCE J, KOLLA, LAXMA R, WEI, CHENKOU, CANN, REGINALD O, LI, JAMES J, LI, JUN
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creator DESHPANDE, RAJENDRA P
WANG, HAIXIA
LI, JIE JACK
QIAN, XINHUA
ROBL, JEFFREY A
GALELLA, MICHAEL
KENNEDY, LAWRENCE J
KOLLA, LAXMA R
WEI, CHENKOU
CANN, REGINALD O
LI, JAMES J
LI, JUN
description Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I: or stereoisomers or pharmaceutically acceptable salts thereof, wherein G, Q, X, Y, R
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
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