Triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors

Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. Th...

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Hauptverfasser: DESHPANDE, RAJENDRA P, WANG, HAIXIA, LI, JIE JACK, QIAN, XINHUA, ROBL, JEFFREY A, GALELLA, MICHAEL, KENNEDY, LAWRENCE J, KOLLA, LAXMA R, WEI, CHENKOU, CANN, REGINALD O, LI, JAMES J, LI, JUN
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Sprache:eng
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Zusammenfassung:Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I: or stereoisomers or pharmaceutically acceptable salts thereof, wherein G, Q, X, Y, R