(7h-pyrrolo [2, 3-d] pyrimidin-4-yl) -piperazines as kinase inhibitors for the treatment of cancer and inflammation

(7h-pyrrolo [2, 3-d] pyrimidin-4-yl) -piperazines as kinase inhibitors for the treatment of cancer and inflammation

Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions com sin them and methods of their use. X is O or NR

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Bibliographische Detailangaben
Hauptverfasser: MABON, ROSS, RAWLINS, DAVID BRENT, RICE, DENNIS S, HARRISON, BRYCE ALDEN, KIMBALL, SPENCER DAVID, ZHANG, YULIAN, VORONKOV, MICHAEL VICTOR
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions com sin them and methods of their use. X is O or NR