Optimized Fc variants and methods for their generation

P:0PER\HPM\Xncor\30690695\SpePages doc-16/12/2008 The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.

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Bibliographische Detailangaben
Hauptverfasser: KARKI, SHER BAHADUR, CHIRINO, ARTHUR J, DESJARLAIS, JOHN RUDOLPH, LAZAR, GREGORY ALAN, DOBERSTEIN, STEPHEN KOHL, HAYES, ROBERT J, VAFA, OMID, DANG, WEI
Format: Patent
Sprache:eng
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Zusammenfassung:P:0PER\HPM\Xncor\30690695\SpePages doc-16/12/2008 The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.