Transdermal delivery devices assuring an improved release of an active principle through a biological interface

Systems, devices, and methods for transdermal delivery of one or more therapeutic active agents to a biological interface. A transdermal drug delivery system is provided for passive transdermal delivery of one or more ionizable active agents to a biological interface of a subject. A transdermal drug...

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Hauptverfasser: YOUHEI NOMOTO, AKIYOSHI SAITO, KIYOSHI KANAMURA, MAYUKO ISHIDA, CHIZUKO ISHIKAWA, IZUMI ISHIKAWA
Format: Patent
Sprache:eng
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Zusammenfassung:Systems, devices, and methods for transdermal delivery of one or more therapeutic active agents to a biological interface. A transdermal drug delivery system is provided for passive transdermal delivery of one or more ionizable active agents to a biological interface of a subject. A transdermal drug delivery system includes a backing substrate, and an active agent layer. The active layer includes a thickening agent, a plasticizer, and a therapeutically effective amount of an ionizable active agent.