5-lipoxygenase-activating protein (FLAP) inhibitors

5-lipoxygenase-activating protein (FLAP) inhibitors

Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory,...

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Bibliographische Detailangaben
Hauptverfasser: SEIDERS, THOMAS JON, HUTCHINSON, JOHN HOWARD, STEARNS, BRIAN ANDREW, EVANS, JILLIAN F, SCOTT, JILL MELISSA, ROPPE, JEFFREY ROGER, LI, YIWEI, PRASIT, PETPIBOON PEPPI, HADDACH, MUSTAPHA, ZUNIC, JASMINE ELEANOR, MORAN, MARK, STOCK, NICHOLAS SIMON, ARRUDA, JEANNIE M, TRUONG, YEN PHAM, WANG, BOWEI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.