Diaryl ethers as opioid receptor antagonist

A compound of the formula (I) wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obe...

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Hauptverfasser: WILLIAM GLEN HOLLOWAY, KUMIKO TAKEUCHI, ELIZABETH MARIE THOMAS, JAMES EDWARD MATT JUNIOR, MILES GOODMAN SIEGEL, MARTA GARCIA DE LA TORRE, NURIA DIAZ BUEZO, DANA RAE SMITH, JAMES ERWIN FRITZ, CONCEPCION PEDREGAL-TERCERO, MARIA-JESUS BLANCO-PILLADO, STEVEN JAMES QUIMBY, RUSSELL DEAN STUCKY, CHAD NOLAN WOLFE, CHARLES HOWARD MITCH, MARK DONALD CHAPPELL
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Sprache:eng
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Zusammenfassung:A compound of the formula (I) wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.