Inhibitors of the hedgehog pathway

Inhibitors of the hedgehog pathway

The present invention is directed to a compound of Formula (I) or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RIDGWAY, BRIAN HUGH, WANG, YONG, BAJJALIEH, WILLIAM, TESFAI, ZEROM, HUYNH, TAI PHAT, FORSYTH, TIMOTHY PATRICK, MANN, GRACE, CHEN, JEFF, SHI, XIAN, TAKEUCHI, CRAIG STACY, MAC, MORRISON B, SANGALANG, JOAN C, MARLOWE, CHARLES K, KIM, BYUNG GYU, EPSHTEYN, SERGEY, BAHCECI, SULEYMAN, LEAHY, JAMES W, LEE, MATTHEW SANGYUP, LEWIS, GARY L
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention is directed to a compound of Formula (I) or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of Formula (I) to treat cancer.