Co-crystals and pharmaceutical compositions comprising the same

The invention relates to compositions and co-crystals each comprising VX-950 and a co-crystal former selected from the group consisting of 4-hydroxybenzoic acid, 4-amino salicylic acid, phenylalanine, threonline, tartaric acid, adipic acid, succinic acetate, proline, methyl 4-hydroxybenzoate, anthra...

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Bibliographische Detailangaben
Hauptverfasser: JURKAUSKAS, VALDAS, JOHNSTON, STEVE, CONNELLY, PATRICK R, ZHANG, YUEGANG, ROSE, PETER, KADIYALA, IRINA, STAVROPOLUS, KATHY, BHISETTI, GOVINDA RAO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to compositions and co-crystals each comprising VX-950 and a co-crystal former selected from the group consisting of 4-hydroxybenzoic acid, 4-amino salicylic acid, phenylalanine, threonline, tartaric acid, adipic acid, succinic acetate, proline, methyl 4-hydroxybenzoate, anthranilic acid, and d-Biotin. Also within the scope of this invention are methods of making and using the same.