Process for the preparation of abacavir
Process for removal of the amino protective group of a N-acylated {(1S,4R)-4- [2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl}methanol of formula (II) where R = H or a (C1-C4)-alkyl, using an inorganic base in a mixture of water and alcohol, to yield abacavir or its salts. The process...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | JULIO CAMPON PARDO RAMON BERENGUER MAIMO JORGE MEDRANO RUPEREZ LAIA ELIAS RIUS |
| description | Process for removal of the amino protective group of a N-acylated {(1S,4R)-4- [2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl}methanol of formula (II) where R = H or a (C1-C4)-alkyl, using an inorganic base in a mixture of water and alcohol, to yield abacavir or its salts. The process proceeds very fast and the product can be obtained in high yield and purity. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2007301934A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2007301934A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2007301934A13</originalsourceid><addsrcrecordid>eNrjZFAPKMpPTi0uVkjLL1IoyUhVKChKLUgsSizJzM9TyE9TSExKTE4syyziYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxjqFGBgbmxgaGlsYmjobGxKkCACyRKJI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Process for the preparation of abacavir</title><source>esp@cenet</source><creator>JULIO CAMPON PARDO ; RAMON BERENGUER MAIMO ; JORGE MEDRANO RUPEREZ ; LAIA ELIAS RIUS</creator><creatorcontrib>JULIO CAMPON PARDO ; RAMON BERENGUER MAIMO ; JORGE MEDRANO RUPEREZ ; LAIA ELIAS RIUS</creatorcontrib><description>Process for removal of the amino protective group of a N-acylated {(1S,4R)-4- [2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl}methanol of formula (II) where R = H or a (C1-C4)-alkyl, using an inorganic base in a mixture of water and alcohol, to yield abacavir or its salts. The process proceeds very fast and the product can be obtained in high yield and purity.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080403&DB=EPODOC&CC=AU&NR=2007301934A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20080403&DB=EPODOC&CC=AU&NR=2007301934A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JULIO CAMPON PARDO</creatorcontrib><creatorcontrib>RAMON BERENGUER MAIMO</creatorcontrib><creatorcontrib>JORGE MEDRANO RUPEREZ</creatorcontrib><creatorcontrib>LAIA ELIAS RIUS</creatorcontrib><title>Process for the preparation of abacavir</title><description>Process for removal of the amino protective group of a N-acylated {(1S,4R)-4- [2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl}methanol of formula (II) where R = H or a (C1-C4)-alkyl, using an inorganic base in a mixture of water and alcohol, to yield abacavir or its salts. The process proceeds very fast and the product can be obtained in high yield and purity.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAPKMpPTi0uVkjLL1IoyUhVKChKLUgsSizJzM9TyE9TSExKTE4syyziYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxjqFGBgbmxgaGlsYmjobGxKkCACyRKJI</recordid><startdate>20080403</startdate><enddate>20080403</enddate><creator>JULIO CAMPON PARDO</creator><creator>RAMON BERENGUER MAIMO</creator><creator>JORGE MEDRANO RUPEREZ</creator><creator>LAIA ELIAS RIUS</creator><scope>EVB</scope></search><sort><creationdate>20080403</creationdate><title>Process for the preparation of abacavir</title><author>JULIO CAMPON PARDO ; RAMON BERENGUER MAIMO ; JORGE MEDRANO RUPEREZ ; LAIA ELIAS RIUS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2007301934A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2008</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>JULIO CAMPON PARDO</creatorcontrib><creatorcontrib>RAMON BERENGUER MAIMO</creatorcontrib><creatorcontrib>JORGE MEDRANO RUPEREZ</creatorcontrib><creatorcontrib>LAIA ELIAS RIUS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JULIO CAMPON PARDO</au><au>RAMON BERENGUER MAIMO</au><au>JORGE MEDRANO RUPEREZ</au><au>LAIA ELIAS RIUS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Process for the preparation of abacavir</title><date>2008-04-03</date><risdate>2008</risdate><abstract>Process for removal of the amino protective group of a N-acylated {(1S,4R)-4- [2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl}methanol of formula (II) where R = H or a (C1-C4)-alkyl, using an inorganic base in a mixture of water and alcohol, to yield abacavir or its salts. The process proceeds very fast and the product can be obtained in high yield and purity.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_AU2007301934A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | Process for the preparation of abacavir |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T08%3A37%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=JULIO%20CAMPON%20PARDO&rft.date=2008-04-03&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU2007301934A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |