Refolding of recombinant proteins

Processes are provided for recovering and purifying refolded recombinant proteins produced in heterologous host cells, which includes the step of refolding the protein in a high pH buffer.

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Bibliographische Detailangaben
Hauptverfasser: SANCHEZ, AILEN, SCHMELZER, CHARLES H, PIZARRO, SHELLY
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Processes are provided for recovering and purifying refolded recombinant proteins produced in heterologous host cells, which includes the step of refolding the protein in a high pH buffer.