Compounds for the treatment of spinal muscular atrophy and other uses

Compounds of Formula (I) or (Il) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mut...

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Hauptverfasser: FAIRFAX, DAVID, MCCALL, JOHN M, JOHNSON, MATTHEW ROBERT, BARNES, KEITH D, HEEMSKERK, JILL, JOHNSON, GRAHAM
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creator FAIRFAX, DAVID
MCCALL, JOHN M
JOHNSON, MATTHEW ROBERT
BARNES, KEITH D
HEEMSKERK, JILL
JOHNSON, GRAHAM
description Compounds of Formula (I) or (Il) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Compounds for the treatment of spinal muscular atrophy and other uses
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