Compounds for the treatment of spinal muscular atrophy and other uses

Compounds for the treatment of spinal muscular atrophy and other uses

Compounds of Formula (I) or (Il) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mut...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FAIRFAX, DAVID, MCCALL, JOHN M, JOHNSON, MATTHEW ROBERT, BARNES, KEITH D, HEEMSKERK, JILL, JOHNSON, GRAHAM
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Compounds of Formula (I) or (Il) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.