Stabilized pharmaceutical composition

It is intended to provide a pharmaceutical composition containing an azole compound which is stable and useful as an antifungal drug. According to the invention, the object could be achieved by adding a basic compound such as magnesium carbonate hydroxide, triethylamine or arginine to the azole comp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HARADA, TSUTOMU, ISHIMOTO, HAYATO, OMAE, HIROSHI
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:It is intended to provide a pharmaceutical composition containing an azole compound which is stable and useful as an antifungal drug. According to the invention, the object could be achieved by adding a basic compound such as magnesium carbonate hydroxide, triethylamine or arginine to the azole compound which is unstable to acid. The pharmaceutical composition is stable without causing degradation of the compound even if a condition such as temperature or humidity is changed during production or storage. Further, it is useful as a therapeutic agent for deep mycosis because systemic administration thereof can be achieved by applying it to an oral agent or an injectable agent.