Use of gallium to treat biofilm-associated infectons

The invention provides methods, compositions, and kits for treatment or prevention of biofilm-associated infections in an individual. Methods of the invention include administration of a gallium-containing composition for treatment of an established biofilm or prevention of formation of a biofilm. S...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SUNIL SREEDHARAN, SUSAN SCHWENDNER, LOUIS R. BUCALO, UWE F. WIRTZ
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides methods, compositions, and kits for treatment or prevention of biofilm-associated infections in an individual. Methods of the invention include administration of a gallium-containing composition for treatment of an established biofilm or prevention of formation of a biofilm. Some methods include administration of a gallium-containing composition in conjunction with an antibiotic substance. Some methods include treatment or prevention of an orally-associated biofilm with a gallium-containing composition in the form of a dentrifice, mouthwash, or chewing gum composition.