Pyrimidinones as casein kinase II (CK2) modulators

A compound according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R6, R7 and Z are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.

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Hauptverfasser: ARLYN ARCALAS, JOERG BUSSENIUS, JEAN-CLAIRE LIMUN MANALO, CHARLES M. BLAZEY, WAI KI VICKY CHAN, NEEL KUMAR ANAND, PATRICK KEARNEY, PEIWEN ZHOU, TSZE H. TSANG, SERGEY EPSHTEYN, CSABA J. PETO, ABIGAIL R. KENNEDY, HONGWANG DU, MOHAMED ABDULKADER IBRAHIM, MOON HWAN KIM, AMY LEW TSUHAKO, KENNETH D. RICE
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creator ARLYN ARCALAS
JOERG BUSSENIUS
JEAN-CLAIRE LIMUN MANALO
CHARLES M. BLAZEY
WAI KI VICKY CHAN
NEEL KUMAR ANAND
PATRICK KEARNEY
PEIWEN ZHOU
TSZE H. TSANG
SERGEY EPSHTEYN
CSABA J. PETO
ABIGAIL R. KENNEDY
HONGWANG DU
MOHAMED ABDULKADER IBRAHIM
MOON HWAN KIM
AMY LEW TSUHAKO
KENNETH D. RICE
description A compound according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R6, R7 and Z are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.
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recordid cdi_epo_espacenet_AU2006304874A1
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Pyrimidinones as casein kinase II (CK2) modulators
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