Pyrimidinones as casein kinase II (CK2) modulators

A compound according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R6, R7 and Z are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.

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Hauptverfasser: ARLYN ARCALAS, JOERG BUSSENIUS, JEAN-CLAIRE LIMUN MANALO, CHARLES M. BLAZEY, WAI KI VICKY CHAN, NEEL KUMAR ANAND, PATRICK KEARNEY, PEIWEN ZHOU, TSZE H. TSANG, SERGEY EPSHTEYN, CSABA J. PETO, ABIGAIL R. KENNEDY, HONGWANG DU, MOHAMED ABDULKADER IBRAHIM, MOON HWAN KIM, AMY LEW TSUHAKO, KENNETH D. RICE
Format: Patent
Sprache:eng
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Zusammenfassung:A compound according to Formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R6, R7 and Z are as defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.