Metallo-beta-lactamase inhibitor
A new metallo-²-lactamase inhibitor which acts as a medicament for inhibiting the inactivation of ²-lactam antibiotics and recovering anti-bacterial activities is disclosed. The maleic acid derivatives having the general formula (I) have metallo-²-lactamase inhibiting activities. It is possible to r...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | A new metallo-²-lactamase inhibitor which acts as a medicament for inhibiting the inactivation of ²-lactam antibiotics and recovering anti-bacterial activities is disclosed. The maleic acid derivatives having the general formula (I) have metallo-²-lactamase inhibiting activities. It is possible to recover the anti-bacterial activities of ²-lactam antibiotics against metallo-²-lactamase producing bacteria by combining the compound of the general formula (I) with ²-lactam antibiotics. |
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