GSK-3 inhibitors

GSK-3 inhibitors

The invention relates to urea derivatives of formula (I) as inhibitors of glycogen synthase kinase 3ß, GSK-3, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which GSK-3 is involved,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ALONSO CASCON, MERCEDES, CASTRO MORERA, ANA, NAVARRO RICO, MARIA LUISA, PEREZ PUERTO, MARIA JOSE, MARTINEZ GIL, ANA, MEDINA PADILLA, MIGUEL, FUERTES HUERTA, ANA, MARTIN APARICIO, ESTER
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The invention relates to urea derivatives of formula (I) as inhibitors of glycogen synthase kinase 3ß, GSK-3, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use for the treatment and or prophylaxis of a disease in which GSK-3 is involved, such as Alzheimer's disease or non-insulin dependent diabetes mellitus.