Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl derivatives and their use as potassium channel blockers

Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl derivatives and their use as potassium channel blockers

Cardiovascular active compounds of the general formula (I), wherein R, R, R, R, R, R, R, R, R, R and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositio...

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Hauptverfasser: MARRISON, LESTER, WESKE, MICHAEL, ZIEGLER, DIETER, FISCHER, YVAN, MLINARIC, MICHAEL, MOLONEY, BRIAN, WITTE, KLAUS, BRUECKNER, REINHARD, BOECKER, CHRISTIANE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Cardiovascular active compounds of the general formula (I), wherein R, R, R, R, R, R, R, R, R, R and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositions comprising the compounds of Formula (I) are specified.