Improved oxidation process with enhanced safety and use thereof

The present invention provides a safe and effective process for the selective oxidation of a 5-O-protected-LLF-28249-alpha compound to the corresponding 23-keto compound of formula I wherein R is a protecting group. The present invention also provides the use of the selective oxidation process in th...

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Bibliographische Detailangaben
Hauptverfasser: PASQUALE MASSARA, GUISEPPE MIRAGLIA, MARCO CARACO, JIGNESH PATEL, STEFANIA SAPIENZA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a safe and effective process for the selective oxidation of a 5-O-protected-LLF-28249-alpha compound to the corresponding 23-keto compound of formula I wherein R is a protecting group. The present invention also provides the use of the selective oxidation process in the manufacture of moxidectin.