Gram positive bacterial cells comprising a disrupted flagellin gene, flagellin-based fusion proteins and use in removal of metal ions from a liquid

Gram positive bacterial cells comprising a disrupted flagellin gene, flagellin-based fusion proteins and use in removal of metal ions from a liquid

The invention provides flagellin-based fusion proteins (FBFP) useful for a variety of purposes, nucleic acids encoding the FBFP, vectors containing the nucleic acids, and host cells harboring the vectors. Furthermore, the invention provides methods for obtaining over-expression and surface display o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CRAMPTON, MICHAEL CRAIG, LOUW, MAUREEN ELIZABETH, BERGER, ELDIE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention provides flagellin-based fusion proteins (FBFP) useful for a variety of purposes, nucleic acids encoding the FBFP, vectors containing the nucleic acids, and host cells harboring the vectors. Furthermore, the invention provides methods for obtaining over-expression and surface display of heterologous polypeptides in Gram-positive bacterial cells. In addition, the invention features gene-disrupted bacteria useful for expressing the recombinant FBFP on their surfaces. Also included in the invention are genetic constructs useful for making FBFP and methods of using the FBFP.