Oral immediate release formulation of a poorly watersoluble active substance

Oral immediate release formulation of a poorly watersoluble active substance

The invention is related to an oral immediate release formulation of Benzazepin -1- acetic acid derivatives comprising: a) said active substance in an amount of up to 65% of the total weight of the formulation; b) at least 10% w/w an alkaline compound or a mixture of alkaline compounds; c) between 0...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MARIUS L. DE WINTER, ROHIT KUMAR, RAJESH JAIN, SUKHJEET SINGH
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The invention is related to an oral immediate release formulation of Benzazepin -1- acetic acid derivatives comprising: a) said active substance in an amount of up to 65% of the total weight of the formulation; b) at least 10% w/w an alkaline compound or a mixture of alkaline compounds; c) between 0.1 and 10% of one or more surfactants, and d) optionally comprises auxiliary materials an amount of between 1% and 45% of the total weight of the formulation.