Imine compound

An imine compound represented by the formula: wherein A represents a heterocyclic group; R 1 , R 2 , an R 3 each represent a hydrogen atom, a halogen atom, a C 1-10 alkyl group optionally substituted with an aryl group(s) substituted with a halogen atom (s), a C 3-10 cycloalkyl group, a C 1-6 haloal...

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Hauptverfasser: YASUMITSU TOMISHIMA, TAKAO YOSHIMIZU, SHINGO SEKINE, YUJI YOKOBORI, MITSUKANE YOSHINAGA, TOMOMI MURAKAMI, TOMOKO ISHIZAKA, KIMIKO TOKUGAWA, AKI MORITA, HIROMITSU YOSHIMURA, MAKOTO TATSUZUKI, HIROSHI OHTA, SHIUJI SAITO, YOSHIHISA TODA, AYAKA KAKU
Format: Patent
Sprache:eng
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Zusammenfassung:An imine compound represented by the formula: wherein A represents a heterocyclic group; R 1 , R 2 , an R 3 each represent a hydrogen atom, a halogen atom, a C 1-10 alkyl group optionally substituted with an aryl group(s) substituted with a halogen atom (s), a C 3-10 cycloalkyl group, a C 1-6 haloalkyl group, a C 1-10 alkoxy group, etc.; R 4 represents an optionally substituted C 1-10 alkyl, C 2-6 alkenyl, or aryl group; R 5 represents a hydrogen atom, a C 1-10 alkoxy group, a C 1-6 haloalkyl group, an optionally substituted C 1-10 alkyl or C 2-6 alkenyl group, an optionally substituted aryl or heterocyclic group, etc.; W represents -CO-, -CO-CO-, -CO-NH-, -CS-NH-, or -SO 2 -, or a cannabinoid-receptor agonist comprising said imine compound as an active ingredient. The imine compound of the present invention has a cannabinoid-receptor agonist effect, and is useful as a therapeutic or prophylactic drug for pains and autoimmune diseases.