Microemulsion and sub-micron emulsion process and compositions

An oil in water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient comprising an oil phase dispersed throughout a water phase, said oil phase including at least one of the group consisting of animal, mineral or vegetable oils, sila...

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Bibliographische Detailangaben
Hauptverfasser:	ALBERT ABRAM, PREMA VIJAYAKUMAR, PHOEBE SUN, MARIA GRAZIELLA LARM, RONALD HARDING, MICHAEL JOHNSTON
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE MIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS TRANSPORTING
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Beschreibung
Zusammenfassung:	An oil in water microemulsion or sub-micron emulsion composition for dermal delivery of at least one pharmaceutically active ingredient comprising an oil phase dispersed throughout a water phase, said oil phase including at least one of the group consisting of animal, mineral or vegetable oils, silanes, siloxanes, esters, fatty acids, fats, halogen compounds, and alkoxylated alcohols; and at least one lipophilic surfactant; and said water phase including at least one hydrophilic surfactant, water and optionally non-surfactant amphiphilic compound, the weight ratio of the at least one hydrophilic surfactant to the at least one lipophilic surfactant being approximately 9.0:1.0 to 2.0:3.0.