Enhancement of antitubercular activity of extracts of salicornia brachiata

The present invention relates to enhancement of anti-tubercular activity of active fraction isolated from Salicornia brachiata. The invention also discloses the non-toxic nature of the fraction and positively identifies Sucrose as its main constituent. Pure Sucrose is shown to have no anti-tubercula...

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Hauptverfasser: MARIAPPANADAR VIRAMANI, BRAHM SHANKAR SRIVASTAVA, MEENA RAJNIKANT RATHOD, PUSPITO KUMAR GHOSH, PRAKASH JAGJIVANBHAI DODIA, ANIL SRIVASTAVA, BHUPENDRA DHANVANTRAI SHETHIA, JAYANT BATUKRAI PANDYA, VINITA CHATURVEDI, RANJANA SRIVASTAVA
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to enhancement of anti-tubercular activity of active fraction isolated from Salicornia brachiata. The invention also discloses the non-toxic nature of the fraction and positively identifies Sucrose as its main constituent. Pure Sucrose is shown to have no anti-tubercular activity indicating thereby that activity of the fraction resides in one or more of the minor constituents. The minor constituents are shown to be relatively low molecular weight entities and a chromatographic technique is disclosed for separating them from the bulk sucrose to probe their activities and structures in detail, as also the possibility of their synthesis if the leads thrown up are novel.