Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators

The present invention provides substituted thiazole and pyrimidine derivatives of Formula (I), methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I), and methods of use in treating human or animal disorders. The compounds of the invention can be useful as...

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Bibliographische Detailangaben
Hauptverfasser:	ANDREWS, ROBERT C, DANKWARDT, JOHN, MJALLI, ADNAN M. M, ZHU, JEFF, ARIMILLI, MURTY N, QABAJA, GHASSAN, SUBRAMANIAN, GOVINDAN, TIAN, YE E, VICTORY, SAMUEL, GADDAM, BAPU R
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides substituted thiazole and pyrimidine derivatives of Formula (I), methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I), and methods of use in treating human or animal disorders. The compounds of the invention can be useful as inhibitors of action of AgRP on a melanocortin receptor and thus can be useful for the management, treatment, control, or the adjunct treatment of diseases which may be responsive to the modulation of melanocortin receptors including obesity-related disorders.