Indene derivatives and process for the preparation thereof
The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic sy...
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creator | SUNG-EUN YOO SUNG DAE PARK JIN HEE AHN HYE JUNG KANG WON HOON JUNG SUN MEE KIM HYAE GYEONG CHEON KOUN HO LEE NAM GEE KIM SUNG SOO KIM JEONG-HYUNG LEE SEUNG JUN KIM SEUNG KYU KANG JAE MOK LEE SUNG-DON YANG SANG DAL RHEE KWANG-ROK KIM JONG HOON KIM KIL WOONG MO |
description | The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer. |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
title | Indene derivatives and process for the preparation thereof |
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