Indene derivatives and process for the preparation thereof

The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic sy...

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Hauptverfasser: SUNG-EUN YOO, SUNG DAE PARK, JIN HEE AHN, HYE JUNG KANG, WON HOON JUNG, SUN MEE KIM, HYAE GYEONG CHEON, KOUN HO LEE, NAM GEE KIM, SUNG SOO KIM, JEONG-HYUNG LEE, SEUNG JUN KIM, SEUNG KYU KANG, JAE MOK LEE, SUNG-DON YANG, SANG DAL RHEE, KWANG-ROK KIM, JONG HOON KIM, KIL WOONG MO
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creator SUNG-EUN YOO
SUNG DAE PARK
JIN HEE AHN
HYE JUNG KANG
WON HOON JUNG
SUN MEE KIM
HYAE GYEONG CHEON
KOUN HO LEE
NAM GEE KIM
SUNG SOO KIM
JEONG-HYUNG LEE
SEUNG JUN KIM
SEUNG KYU KANG
JAE MOK LEE
SUNG-DON YANG
SANG DAL RHEE
KWANG-ROK KIM
JONG HOON KIM
KIL WOONG MO
description The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and thus, they are useful for the treatment and prevention of disorders modulated by PPARs, i.e., metabolic syndromes such as diabetes, obesity, arteriosclerosis, hyperlipidemia, hyperinsulinism and hypertension, inflammatory diseases such as osteoporosis, liver cirrhosis and asthma, and cancer.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Indene derivatives and process for the preparation thereof
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