Method of preparing low-crystallinity oltipraz or amorphous oltipraz

Method of preparing low-crystallinity oltipraz or amorphous oltipraz

Provided is a method of preparing low-crystallinity oltipraz or amorphous oltipraz. The method includes: obtaining a mixed solution containing oltipraz and a water-soluble polymer or a water-insoluble polymer in a solvent, the solvent being an organic solvent or purified water; and solid-dispersing...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: JAE-MOOK CHOI, HYUN-JUNG PARK, TAE-HYOUNG KIM, KYOUNG-RAE KANG, TAE-KUN AN, HAE-TAK JIN, HYESUK HONG, IL-HWAN KIM, CHEONG-WEON CHO, SUNG-HAK LEE, IN-KI MIN, JUN-HEE CHEON, EUN-KYUNG JEON, JINWAN KIM, KWANG-HEE HONG, NAK-HYUN CHOI, SANG-HO LEE, KYU-JEONG YEON, TAEKRHO KIM, YOUNG-HOON KIM, JEE-WOONG LIM, KWANG-DO CHOI, HEARAN SUH, JEONG KU
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Provided is a method of preparing low-crystallinity oltipraz or amorphous oltipraz. The method includes: obtaining a mixed solution containing oltipraz and a water-soluble polymer or a water-insoluble polymer in a solvent, the solvent being an organic solvent or purified water; and solid-dispersing the oltipraz in the polymer. In the solid-dispersing, the mixed solution may be spray dried using a spray dryer or granulated using a fluid bed granulator.