Fibrinogen purlfication

ZLB BEHRING GMBH 2004/M002 (AB3) Fibrinogen purification Abstract The present invention relates to a process for purifying fibrinogen, which comprises one or more process steps in which one or more contaminating proteins are depleted by negative chromatography and/or negative adsorption using cation...

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Bibliographische Detailangaben
Hauptverfasser:	LIEBING, UWE, FEUSSNER, ANNETTE, SCHULTE, STEFAN, LEMMER, JOERG, METZNER, HUBERT, GAWANTKA, VOLKER
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	ZLB BEHRING GMBH 2004/M002 (AB3) Fibrinogen purification Abstract The present invention relates to a process for purifying fibrinogen, which comprises one or more process steps in which one or more contaminating proteins are depleted by negative chromatography and/or negative adsorption using cation exchanger, hydrophobic gel and/or dye gel. in addition, the invention relates to the fibrinogen which is obtained by the process of the invention and which is notable for improved stability, and to the production and use of pharmaceutical preparations comprising this fibrinogen.