Preparation of 3-azabicyclo (3.1.0) hexane derivatives

Preparation of 3-azabicyclo (3.1.0) hexane derivatives

This present invention relates to a new and improved reductive amination process for the preparation of 3-azabicyclo[3.1.0]hexane derivatives and pharmaceutical compositions comprising such derivatives. The invention particularly relates to using such derivatives to treat certain disorders and condi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DEREK LAWRENCE TICKNER, JOTHAM WADSWORTH COE, STANTON FURST MCHARDY, BRIAN CLEMENT VANDERPLAS, JOHN ANTHONY RAGAN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:This present invention relates to a new and improved reductive amination process for the preparation of 3-azabicyclo[3.1.0]hexane derivatives and pharmaceutical compositions comprising such derivatives. The invention particularly relates to using such derivatives to treat certain disorders and conditions, including, for example, irritable bowel syndrome, drug addiction or dependency, alcohol addiction or dependency, depression, and eating disorders.