Process for the production of tibolone

Disclosed is a process for the synthesis of 17²-hydroxy-7±-methyl- 19-nor-17±-pregn-5(10)-ene-20-yne-3-one (tibolone, 11) and intermediates useful for the synthesis thereof: (11).

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Bibliographische Detailangaben
Hauptverfasser: DEREK MCHATTIE, ALAN KENNETH GREENWOOD, PARVEEN BHATARAH
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed is a process for the synthesis of 17²-hydroxy-7±-methyl- 19-nor-17±-pregn-5(10)-ene-20-yne-3-one (tibolone, 11) and intermediates useful for the synthesis thereof: (11).