Aminoheteroaryl compounds as protein kinase inhibitors

Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.

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Bibliographische Detailangaben
Hauptverfasser:	FANG-JIE ZHANG, MITCHELL DAVID NAMBU, MASON ALAN PAIRISH, JASON(QISHEN) LIN, JERRY JIALUN MENG, LEE A. FUNK, JOANNE JOHNSON, ALISON WALTER, PEI-PEI KUNG, CHRISTOPHER G. NELSON, JINGJONG JEAN CUI, DILIP BHUMRALKAR, CATHLEEN ELIZABETH HANAU, G. DAVIS HARRIS JR, XIAOYUAN(SHARON) LI, IRINY BOTROUS, MICHELLE TRAN-DUBE, STEPHEN A. KOLODZIEJ, LEI JIA, JI YU CHU, HONG SHEN, ZENNIFER ZHANG
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Aminopyridine and aminopyrazine compounds of formula (1), compositions including these compounds, and methods of their use are provided. Preferred compounds of formula 1 have activity as protein kinase inhibitors, including as inhibitors of c-MET.