Nanoparticulate fibrate formulations

The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.

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Bibliographische Detailangaben
Hauptverfasser: EVAN E. GUSTOW, RAKESH PATEL, RAJEEV JAIN, STEPHEN B. RUDDY, MICHAEL JOHN WILKINS, TUULA RYDE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective average particle size of less than about 2000 nm.