BACTERIAL VIRULENCE GENES

The application provides an attenuated Actinobacillus pleuropneumoniae bacterium having a mutation in a gene required for bacterial virulence, wherein said gene comprises the nucleotide sequence SEQ ID NO: 10. The application also provides an attenuated Actinobacillus pleuropneumoniae bacterium havi...

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Bibliographische Detailangaben
Hauptverfasser: PAUL, RICHARD LANGFORD, JANINE BOSSE, ANDREW RYCROFT, BRIAN SHEEHAN, AMANDA BEDDEK, JOHN, SIMON KROLL
Format: Patent
Sprache:eng
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Zusammenfassung:The application provides an attenuated Actinobacillus pleuropneumoniae bacterium having a mutation in a gene required for bacterial virulence, wherein said gene comprises the nucleotide sequence SEQ ID NO: 10. The application also provides an attenuated Actinobacillus pleuropneumoniae bacterium having a mutation in a nucleic acid sequence responsible for, or involved in, controlling expression of a gene required for bacterial virulence, wherein said nucleic acid sequence comprises the nucleotide sequence SEQ ID NO: 47.