THE GENE CLUSTER INVOLVED IN SAFRACIN BIOSYNTHESIS AND ITS USES FOR GENETIC ENGINEERING

A gene cluster is disclosed having open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule. In addition, the present disclosure is directed to a nucleic acid sequence, suitably an isolated nucleic acid sequence, which includes or comprises at least SEQ...

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Bibliographische Detailangaben
Hauptverfasser:	FERNANDO DE LA CALLE, PILAR RODRIGUEZ RAMOS, FERNANDO REYES BENITEZ, ANA VELASCO IGLESIAS, PALOMA ACEBO PAIS, RUBEN HENRIQUEZ PELAEZ, CARMEN SCHLEISSNER SANCHEZ, TOMAS APARICIO PEREZ
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A gene cluster is disclosed having open reading frames which encode polypeptides sufficient to direct the synthesis of a safracin molecule. In addition, the present disclosure is directed to a nucleic acid sequence, suitably an isolated nucleic acid sequence, which includes or comprises at least SEQ ID NO:1, variants or portions thereof, or at least one of the sacA, sacB, sacC, sacC, sacD, sacE, sacF, sacG, sacH, sacH, saI, sacJ, orf1, orf2, orf3 or orf4 genes, including variants or portions.